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Robert B Clark Selected Research

Toll-Like Receptor 2

1/2022Gut microbiome-derived glycine lipids are diet-dependent modulators of hepatic injury and atherosclerosis.
1/2021Serine/Glycine Lipid Recovery in Lipid Extracts From Healthy and Diseased Dental Samples: Relationship to Chronic Periodontitis.
12/2020A novel phosphoglycerol serine-glycine lipodipeptide of Porphyromonas gingivalis is a TLR2 ligand.
7/2019Systemic TLR2 tolerance enhances central nervous system remyelination.
2/2012Free lipid A isolated from Porphyromonas gingivalis lipopolysaccharide is contaminated with phosphorylated dihydroceramide lipids: recovery in diseased dental samples.

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Robert B Clark Research Topics

Disease

6Multiple Sclerosis
01/2019 - 12/2009
4Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
07/2019 - 12/2009
4Inflammation (Inflammations)
01/2016 - 03/2002
4Autoimmune Diseases (Autoimmune Disease)
10/2011 - 04/2007
3Atherosclerosis
01/2022 - 01/2017
3Chronic Periodontitis
01/2021 - 12/2015
3Periodontal Diseases (Periodontal Disease)
01/2021 - 09/2010
3Alveolar Bone Loss
12/2020 - 02/2012
2Periodontitis
01/2021 - 12/2015
2Stillbirth
11/2017 - 08/2016
2Neoplasms (Cancer)
01/2017 - 02/2006
2Ventricular Tachycardia
08/2013 - 01/2010
2Eosinophilia
06/2008 - 07/2007
1Atopic Dermatitis (Atopic Eczema)
01/2022
1Chronic Obstructive Pulmonary Disease (COPD)
01/2022
1Psoriatic Arthritis
01/2022
1Psoriasis (Pustulosis Palmaris et Plantaris)
01/2022
1Calculi (Calculus)
01/2021
1Gingivitis
01/2021
1Demyelinating Diseases (Demyelinating Disease)
07/2019
1Lymphoma (Lymphomas)
01/2017
1Hemorrhage
08/2016
1Infections
12/2015
1Alzheimer Disease (Alzheimer's Disease)
11/2013
1Polymorphic catecholergic ventricular tachycardia
08/2013
1Lymphopenia (Lymphocytopenia)
10/2011
1Traumatic Brain Injuries (Traumatic Brain Injury)
08/2010
1Atherosclerotic Plaque (Atheroma)
12/2009
1Hypersensitivity (Allergy)
05/2009
1Leukocytosis (Pleocytosis)
06/2008
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
08/2007
1Type 2 Diabetes Mellitus (MODY)
04/2007
1Graft vs Host Disease (Graft-Versus-Host Disease)
04/2007

Drug/Important Bio-Agent (IBA)

10LipidsIBA
01/2022 - 12/2009
5Serine (L-Serine)FDA Link
01/2022 - 12/2015
5Toll-Like Receptor 2IBA
01/2022 - 02/2012
4LigandsIBA
12/2020 - 03/2002
3DipeptidesIBA
10/2017 - 12/2015
3AerosolsIBA
01/2015 - 07/2007
3PPAR gammaIBA
10/2011 - 03/2002
2Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2022 - 01/2021
2Immunoglobulin E (IgE)IBA
01/2015 - 07/2007
2Peptides (Polypeptides)IBA
09/2013 - 02/2011
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2011 - 03/2002
2AntigensIBA
02/2011 - 05/2009
2Sodium Channels (Sodium Channel)IBA
01/2010 - 08/2007
1Phosphodiesterase 4 InhibitorsIBA
01/2022
1diethylstilbestrol monophosphate (PDES)IBA
01/2022
1Cyclic NucleotidesIBA
01/2022
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
01/2022
1CuprizoneIBA
07/2019
1Phospholipases A2 (Phospholipase A2)IBA
01/2019
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2017
1Pharmaceutical PreparationsIBA
01/2016
1Fingolimod Hydrochloride (FTY720)FDA Link
05/2015
1OvalbuminIBA
01/2015
1CytokinesIBA
01/2015
1Biomarkers (Surrogate Marker)IBA
11/2013
1Chromogranin BIBA
09/2013
1Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
08/2013
1phospholambanIBA
08/2013
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
10/2011
1Myelin-Oligodendrocyte GlycoproteinIBA
02/2011
1Proteins (Proteins, Gene)FDA Link
08/2010
1Methacholine Chloride (Methacholine)FDA Link
06/2008
1ciglitazoneIBA
04/2007
1Transforming Growth Factor beta (TGF-beta)IBA
02/2006
1Transcription Factors (Transcription Factor)IBA
03/2002

Therapy/Procedure

4Therapeutics
01/2022 - 06/2011
1Resuscitation
11/2017
1Immunotherapy
01/2017
1Prenatal Care (Care, Prenatal)
08/2016